Surgery to correct trichiasis is a key component of the World Health Organisation trachoma elimination strategy, however unfavourable outcomes such as eyelid contour abnormalities (ECA) following surgery are relatively common. This study aimed to understand the transcriptional changes associated with the early development of ECA and the impact of doxycycline, which has anti-inflammatory and anti-fibrotic properties, upon these transcription patterns.
This study compares intracellular replication and inclusion development of representative C.trachomatis serovars in immortalized human conjunctival epithelial, urogenital epithelial, PMA stimulated THP-1 (macrophages), and HeLa cells.
This study addressed whether the regional differences in water, sanitation, and hygiene (WASH) variables were associated with the spatial distribution of trachomatous inflammation-follicular (TF) among children aged 1 to 9 years in the Amhara National Regional State of Ethiopia.
The objective of this study was to estimate the potential for fingers that have come in contact with Chlamydia trachomatis-positive urine to detectably contaminate C. trachomatis-negative urine.
This study examined the participants of a clinical trial four years after enrolment to identify which of the two most commonly used eyelid surgery procedures to treat trachomatous trichiasis, the posterior Lamellar Tarsal Rotation (PLTR) and Billamelar Tarsal Rotation (BLTR), gives better results in the long-term.
Using the WHO framework for analysing health systems, this study aims to assess what is known about the current eye health system in Yemen with ongoing conflict.
In this study, impact surveys in six evaluation units of Malawi were used as a platform to explore associations between the prevalence of TF, ocular C. trachomatis infection and anti-Pgp3 antibodies one year after the third annual round of MDA.
The objective of this study was determining the prevalence of active trachoma and associated factors among children aged 1 to 9 years in rural community of Lemo district.
This study aims to determine the effect of MDA for trachoma elimination on M. genitalium prevalence, strain type and azithromycin resistance.