The immuno-pathogenesis of progressive scarring trachoma: results of a four-year longitudinal study in Tanzanian children

This study highlights the importance of innate pro-inflammatory signals from the epithelium and implicate IL -23A -responsive cells in driving trachomatous scarring, with potential key mechanistic roles for PDGFB, MMP12 and SPARCL1 in orchestrating fibrosis. 

Type: 
Research
Language: 
English